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Saturday, February 8, 2020 | History

4 edition of Membrane transporters in drug discovery and development found in the catalog.

Membrane transporters in drug discovery and development

methods and protocols

by Qing Yan

  • 376 Want to read
  • 27 Currently reading

Published by Humana in [Clifton, N.J.] .
Written in English

    Subjects:
  • Carrier proteins,
  • Membrane Transport Proteins,
  • Methods,
  • Drugs,
  • Physiological transport,
  • Drug Discovery,
  • Laboratory Manuals

  • Edition Notes

    Includes bibliographical references and index.

    Statementedited by Qing Yan
    SeriesSpringer protocols, Methods in molecular biology -- 637, Springer protocols, Methods in molecular biology (Clifton, N.J.) -- v. 637.
    Classifications
    LC ClassificationsRM301.55 .M46 2010
    The Physical Object
    Paginationxiii, 363 p. :
    Number of Pages363
    ID Numbers
    Open LibraryOL25296772M
    ISBN 101607616998, 1607617005
    ISBN 109781607616993, 9781607617006
    LC Control Number2010923408
    OCLC/WorldCa495780920

    Shortly hereafter in she initiated the Molecular Biopharmaceutics research group at the University of Pharmaceutical Sciences focusing in the beginning on designing prodrugs for the absorptive peptide transporter PEPT1. Comprehensive and highly practical, Membrane Transporters: Methods and Protocols offers investigators working in biopharmaceutical science, drug discovery, and drug delivery both an array of powerful tools for work on membrane transporters and an essential guide to the state-of-the-art in the membrane transporter field today. Her interest for membrane transporters has since then expanded to include many other transporters. In Membrane Transporters: Methods and Protocols, a panel of recognized basic and clinical investigators-many world-famous-describe their proven, cutting-edge methodologies for studying these important proteins.

    Steffansen has published more than 60 research articles, edited a book, and serves as the program director for pharmaceutical education at the University of Copenhagen. Learn about new offers and get more deals by joining our newsletter Sign up now. About this book Introduction Studies of membrane transporters have had a great impact on our understanding of human diseases and the design of effective drugs. Her interest for membrane transporters has since then expanded to include many other transporters. Wide-ranging and current, Membrane Transporters in Drug Discovery and Development: Methods and Protocols delivers a collection of practical protocols that can be used immediately in the lab, along with critical surveys of key topics by leading researchers in the field.

    The latest understanding of transporter-related drug-drug interactions is included, as well as an industrial perspective of transporters in ADME. She graduated with MSc pharm in from the Royal Danish School of Pharmacy and obtained her PhD in under the Danish Research Academy within the field of prodrug design aimed for improved drug delivery. Download Citation About this book Understanding and quantifying the effects of membrane transporters within the human body is essential for modulating drug safety and drug efficacy. Steffansen has published more than 60 research articles, edited a book, and serves as the program director for pharmaceutical education at the University of Copenhagen.


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Membrane transporters in drug discovery and development by Qing Yan Download PDF Ebook

The latest understanding of transporter-related drug-drug interactions is included, as well as an industrial perspective of transporters in ADME. The topics covered in both volumes ensure that all relevant aspects of transporters are described across the drug development process, from in silico models and preclinical tools through to the potential impact of transporters in the clinic.

The challenges of translating in vitro observed interaction of transporters into in vivo relevance are explored, and the book highlights perspectives of applying targeted proteomics and mechanistic modeling in this process.

Membrane Transporters

Review Text From the book reviews: A collection of chapters from the heavyweights of drug transporters, this book is likely to stand proud on the shelves of anyone in the field.

In she edited a book in Molecular Biopharmaceutis, she is a member of the European BioSim network of excellence, and has received several research grants including honorable travel grant. Her interest for membrane transporters has since then expanded to include many other transporters.

In this article, we provide the recommendations of the International Transporter Consortium on these issues, and present decision trees that are intended to help guide clinical studies on the currently recognized most important drug transporter interactions.

She vent to the University of Uppsala in Sweden as visiting scientist in She vent to Membrane transporters in drug discovery and development book University of Uppsala in Sweden as visiting scientist in Membrane transporters in drug development. The latest understanding of transporter-related Membrane transporters in drug discovery and development book interactions is included, as well as an industrial perspective of transporters in ADME.

She graduated with MSc pharm in from the Royal Danish School of Pharmacy and obtained her PhD in under the Danish Research Academy within the field of prodrug design aimed for improved drug delivery. Her interest for membrane transporters has since then expanded to include many other transporters.

The book describes methods and examples of in vitro characterization of single transporters in the intestines, liver, and kidneys as well as characterization of substrate overlap between various transporters.

The text is very much aimed at those engrossed in the study of transporters and the tools available for their study. Download Citation About this book Understanding and quantifying the effects of membrane transporters within the human body is essential for modulating drug safety and drug efficacy.

The latest understanding of transporter-related drug-drug interactions is included, as well as an industrial perspective of transporters in ADME. Bente has more than 60 research publications, supervised more than Master students for their final research degree and 15 PhD's.

Transporter studies in drug discovery and development for various diseases are discussed, including neuropsychiatric disorders, cardiovascular diseases, ophthalmic diseases, cancer, and diabetes. Steffansen has published more than 60 research articles, edited a book, and serves as the program director for pharmaceutical education at the University of Copenhagen.

The text is very much aimed at those engrossed in the study of transporters and the tools available for their study. She graduated with MSc pharm in from the Royal Danish School of Pharmacy and obtained her PhD in under the Danish Research Academy within the field of prodrug design aimed for improved drug delivery.

Wide-ranging and current, Membrane Transporters in Drug Discovery and Development: Methods and Protocols delivers a collection of practical protocols that can be used immediately in the lab, along with critical surveys of key topics by leading researchers in the field.

In she edited a book in Molecular Biopharmaceutis, she is a member of the European BioSim network of excellence, and has received several research grants including honorable travel grant. Pharmaceutical Technology Back cover copy Transporters in Drug Development examines how membrane transporters can be dealt with in academic-industrial drug discovery and pharmaceutical development as well as from a regulatory perspective.

Each technique contains hands-on instructions, many notes on avoiding the problems that one may encounter, and suggestions for variant procedures. Editors and affiliations. About this book Introduction Transporters in Drug Development examines how membrane transporters can be dealt with in academic-industrial drug discovery and pharmaceutical development as well as from a regulatory perspective.

The recommendations are generally intended to support clinical development and filing of a new drug application. Pharmaceutical Technology Back cover copy Transporters in Drug Development examines how membrane transporters can be dealt with in academic-industrial drug discovery and pharmaceutical development as well as from a regulatory perspective.Transporters in Drug Development examines how membrane transporters can be dealt with in academic-industrial drug discovery and pharmaceutical development as well as from a regulatory perspective.

The book describes methods and examples of in vitro characterization of single transporters in the intestines, liver and kidneys as well as characterization of substrate overlap between various. White Paper: Nature Reviews Drug Discovery Vol 9, p.

Basic Introduction and Summary of Transporter Highlights what we know Methods for Studying Transporters Current solutions and future prospects Drug Development Issues Decision trees.

Membrane Transporters in Drug Development.

Importance of ABC Transporters in Drug Development

The International Transporter Consortium, ITC. SOLVO is pleased to sponsor the dinner presentation on theTransporters in Drug Discovery and Development Course.

Membrane Transporters in Drug Discovery and Development

August 02, Solvo is a Diamond-level sponsor of the University of Rhode Island’s Transporters in Drug Discovery and Development Course in Kingston, RI, where we are pleased to sponsor the dinner presentation: “A look into the strange and confusing world of ADME/transporters.Transporters in Drug Pdf and Development, Kingston.

72 likes. Practical and hands-on course on Transporters in Drug Discovery and Development: Driving Knowledge from Laboratory to magicechomusic.comers: The book encompasses examples and advises on how membrane transporters can download pdf dealt with in academic industrial drug discovery and pharmaceutical development as well as from a regulatory perspective.

Methods and examples of in vitro characterization of single transporters in intestine, liver and kidney are described as well as characterization Brand: Yuichi Sugiyama.This ebook explores the role of transporters in ebook ADME, describing their different mechanisms of action, their location within the body, how different factors can affect transporter form and function, as well as giving a concise overview of some of the key aspects to consider in Author: John Keogh, Bruno Hagenbuch, Caroline Rynn, Bruno Stieger, Glynis Nicholls.